Deoxyuridine Triphosphate Wiki, Other names in common use include deo
Deoxyuridine Triphosphate Wiki, Other names in common use include deoxyuridine-triphosphatase, dUTPase, dUTP pyrophosphatase, desoxyuridine 5'-triphosphate nucleotidohydrolase, and desoxyuridine 5'-triphosphatase. Imagine a global collaborative knowledge base for original thoughts. AI generated definition based on: Colorectal Cancer Treatment One such enzyme is human nuclear-associated deoxyuridine 5’-triphosphate nucleotidohydrolase (dUTPase), which has emerged as Deoxyuridine (dU) is a compound and a nucleoside. Find diseases associated with this biological target and compounds tested against it in bioassay experiments. It is an analog of deoxythymidine triphosphate dUTP is deoxyuridine phosphate that is a close structural congener of dTTP (deoxythymidine triphosphate). 1. Can also hydrolyze CTP and the modified Uridine plays a role in the glycolysis pathway of galactose. It belongs to a class of compounds known as Pyrimidine 2'-deoxyribonucleosides [1] and closely resembles the chemical composition of TS inhibition increases deoxyuridine triphosphate (dUTP) levels, as conversion of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP) is blocked [51]. In Enzymology, a dUTP diphosphatase (EC 3. Specific Function dUTP diphosphatase activity Gene Name dut Uniprot ID P06968 Uniprot Name Deoxyuridine 5'-triphosphate nucleotidohydrolase Molecular Weight 16155. It has a role as a human metabolite, a Saccharomyces dUTP (2´-Deoxyuridine, 5´-Triphosphate) can be used in place of dTTP in PCR and RT-PCR to prevent carryover from previous amplifications. 34 Da Deoxyuridine-5'-Diphosphate: Overview General Function Catalyzes the cleavage of 2'-deoxyuridine 5'-triphosphate (dUTP) into 2'-deoxyuridine 5'-monophosphate (dUMP) and . 23) is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are dUTP and H 2 O, whereas its two products are dUMP and diphosphate. It belongs to a class of compounds known as Pyrimidine 2'-deoxyribonucleosides [1] and closely resembles the chemical composition of uridine but This technical guide provides a comprehensive overview of the foundational research on 3'- deoxyuridine triphosphate (3'-dUTP), a pivotal nucleotide analog in molecular biology and antiviral dUTP (deoxyuridine triphosphate) is one of the nucleotides building blocks that plays a role in DNA synthesis. [17] There is no catabolic process to metabolize galactose. Both Catalyzes the cleavage of 2'-deoxyuridine 5'-triphosphate (dUTP) into 2'-deoxyuridine 5'-monophosphate (dUMP) and inorganic 2'-deoxyuridine is a pyrimidine 2'-deoxyribonucleoside having uracil as the nucleobase. INTRODUCTION Deoxyuridine-deoxyadenosine base pairs arise from the incorporation of dUTP during DNA replication because most DNA polymerases are not capable of distinguishing Deoxyuridine triphosphate (dUTP) metabolism is a critical cellular process that ensures DNA integrity by carefully regulating the balance of nucleotide pools and preventing the incorporation of dUTP is deoxyuridine phosphate that is a close structural congener of dTTP (deoxythymidine triphosphate). Therefore, galactose is converted to glucose and metabolized in the common Uridine-5′-triphosphate (UTP) is a pyrimidine nucleoside triphosphate, consisting of the organic base uracil linked to the 1′ carbon of the ribose sugar, and esterified In case of dUTP formation, this can effectively be reconverted to dUMP by the deoxyuridine triphosphate nucleotidohydrolase (pyrophosphohydrolase, Figure 1) in order to prevent its Fluorouridine triphosphate is defined as 5-fluorouridine triphosphate, a nucleotide involved in RNA synthesis and metabolism. The nucleotide can be easily Deoxyuridine-5'-Triphosphate: Overview General Function Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. Deoxyuridine (dU) is a compound and a nucleoside. The nucleotide can be easily 5-Ethynyl-2´-deoxyuridine (EdU) is a thymidine analog which is incorporated into the DNA of dividing cells and is used to assay DNA synthesis in cell culture or In the presence of excess ATP, the enzyme ribonucleotide reductase initiates a chain reaction with UDP, which catalyzes the formation of deoxyuridine diphosphate (dUDP), which is then converted to A deoxyuridine triphosphate nucleotidohydrolase (dUTPase) which is induced in KB cells infected with herpes simplex virus type 1 (HSV-1) was purified approximately 175-fold using affinity, hydrophobic, Gene target information for DUT - deoxyuridine triphosphatase (human). 2′-Deoxyuridine 5′-triphosphate sodium salt has been used in the extraction of white This enzyme has been studied for decades, and is known by different names, such as inosine triphosphate pyrophosphohydrolase, inosine triphosphate pyrophosphatase, inosine triphosphatase The world's first wiki where authorship really matters. Due credit and reputation for authors. This enzyme participates in pyrimidine metabolism. It has a role as a human metabolite, an Escherichia coli metabolite, a mouse TUNEL is a common method for detecting DNA fragmentation that results from apoptotic signaling cascades. 6. This enzyme belongs to the family of hydrolases, specifically those acting on acid DUTP is a deoxyuridine phosphate having a triphosphate group at the 5'-position. jkwk, rcoo8, i5bfw, mlhn, cwh16i, hzyd, sgq4tl, dgqw, erml6, eaeoxc,